Description
OVERVIEWProduct overview
PT-141 is a cyclic analogue derived from Melanotan II, studied for its activity at central melanocortin receptors rather than at peripheral pigmentation pathways.
Published work concerns MC3R and MC4R pharmacology and central nervous system signalling in animal models.
All published work is preclinical or investigational. This material is supplied as a laboratory reference compound and is not authorised as a medicine in Ireland, the UK or the EU.
SUPPLY IN IRELANDPT-141 Ireland — supplied to research laboratories
Research groups across Ireland buy PT-141 from Kensington Laboratories as a lyophilised PT-141 peptide, released only against a batch-matched certificate of analysis. Every vial of high purity PT-141 is verified by HPLC and LC-MS before it leaves the facility, so laboratories ordering PT-141 in Ireland receive material with documented purity and identity.
Laboratory PT-141 is packed for controlled storage and sent by tracked delivery in 3–5 days to Dublin, Cork, Galway, Limerick and the rest of Ireland. Delivery costs €9.90 per order. Teams planning PT141 research can review the specifications, certificate of analysis and reference list on this page before ordering.
Institutions searching for PT-141 peptide suppliers in Ireland typically compare purity, batch documentation and delivery times. Each of those is published here: a 99% HPLC purity specification, a certificate matched to the batch code on your vial, and tracked delivery in 3–5 days.
PT-141 is supplied strictly for laboratory research use only. It is not a medicine and is not for human or veterinary consumption.
SPECIFICATIONSProduct specifications
- Purity: ≥ 99% (HPLC)
- Appearance: White lyophilised powder
- Quantity: 10 mg per vial
- CAS number: 189691-06-3
- Peptide class: Cyclic heptapeptide analogue of alpha-MSH
- Also known as: Bremelanotide, melanocortin receptor agonist
- Solubility: Soluble in bacteriostatic or sterile water
- Storage temperature: Store at 2–8°C; long-term −20°C, protected from light
- Shelf life: 24 months lyophilised; 30 days reconstituted at 2–8°C
- Manufacturing standard: ISO 9001 facility, GMP-aligned solid-phase synthesis
- Batch information: Batch number and expiry printed on every vial label
RESEARCHResearch overview
The following summary is provided for educational and scientific context only. It describes what has been observed in published laboratory and animal studies and does not represent established clinical outcomes, medical advice or a claim of efficacy in humans.
Background
PT-141 is a cyclic analogue derived from Melanotan II, studied for its activity at central melanocortin receptors rather than at peripheral pigmentation pathways.
Published work concerns MC3R and MC4R pharmacology and central nervous system signalling in animal models.
All published work is preclinical or investigational. This material is supplied as a laboratory reference compound and is not authorised as a medicine in Ireland, the UK or the EU.
Current research areas
Published investigation clusters around a small number of biological themes. Each remains experimental and none has been established as a therapeutic effect in humans.
- MC3R and MC4R receptor binding assays
- Central nervous system signalling studies
- Comparative work against Melanotan II
- Blood pressure and cardiovascular endpoints
Scientific context and proposed mechanisms
Agonism at MC3R and MC4R in the central nervous system is described as the basis for the behavioural endpoints reported, distinguishing it from MC1R-driven pigmentation effects.
Interpreting the evidence
Most published work in this area uses cell culture or rodent models with small group sizes and short observation windows. Independent replication varies considerably between compounds, and results are sensitive to species, route, dose and endpoint.
There is no regulatory-approved human protocol for this compound. Any laboratory protocol should be defined by the model under study, institutional ethical approval, appropriate controls and predefined endpoints.
References
CERTIFICATE OF ANALYSISIndependent batch testing
Every released batch is independently tested. Match the batch number on the vial to the certificate published online.
- Batch number
- KL-PT141-2409A
- Testing laboratory
- Janoshik Analytical, s.r.o.
- Date tested
- 12 August 2026
- Reported purity
- 99.84%
- Method
- RP-HPLC with UV detection at 214 nm, confirmed by LC-MS
