Description
OVERVIEWProduct overview
Semax is a synthetic analogue of the ACTH (4-10) fragment with a C-terminal Pro-Gly-Pro extension that greatly increases its stability, developed by Russian research institutes.
Published work examines BDNF expression, neuroprotection in ischaemia models and cognitive endpoints in rodents.
All published work is preclinical or investigational. This material is supplied as a laboratory reference compound and is not authorised as a medicine in Ireland, the UK or the EU.
SUPPLY IN IRELANDSemax Ireland — supplied to research laboratories
Research groups across Ireland buy Semax from Kensington Laboratories as a lyophilised Semax peptide, released only against a batch-matched certificate of analysis. Every vial of high purity Semax is verified by HPLC and LC-MS before it leaves the facility, so laboratories ordering Semax in Ireland receive material with documented purity and identity.
Laboratory Semax is packed for controlled storage and sent by tracked delivery in 3–5 days to Dublin, Cork, Galway, Limerick and the rest of Ireland. Delivery costs €9.90 per order. Teams planning Semax research can review the specifications, certificate of analysis and reference list on this page before ordering.
Institutions searching for Semax peptide suppliers in Ireland typically compare purity, batch documentation and delivery times. Each of those is published here: a 99% HPLC purity specification, a certificate matched to the batch code on your vial, and tracked delivery in 3–5 days.
Semax is supplied strictly for laboratory research use only. It is not a medicine and is not for human or veterinary consumption.
SPECIFICATIONSProduct specifications
- Purity: ≥ 99% (HPLC)
- Appearance: White lyophilised powder
- Quantity: 5 mg per vial
- Peptide class: Synthetic heptapeptide analogue of adrenocorticotropic hormone fragment 4-10
- Also known as: ACTH (4-10) analogue, Met-Glu-His-Phe-Pro-Gly-Pro
- Solubility: Soluble in bacteriostatic or sterile water
- Storage temperature: Store at 2–8°C; long-term −20°C, protected from light
- Shelf life: 24 months lyophilised; 30 days reconstituted at 2–8°C
- Manufacturing standard: ISO 9001 facility, GMP-aligned solid-phase synthesis
- Batch information: Batch number and expiry printed on every vial label
RESEARCHResearch overview
The following summary is provided for educational and scientific context only. It describes what has been observed in published laboratory and animal studies and does not represent established clinical outcomes, medical advice or a claim of efficacy in humans.
Background
Semax is a synthetic analogue of the ACTH (4-10) fragment with a C-terminal Pro-Gly-Pro extension that greatly increases its stability, developed by Russian research institutes.
Published work examines BDNF expression, neuroprotection in ischaemia models and cognitive endpoints in rodents.
All published work is preclinical or investigational. This material is supplied as a laboratory reference compound and is not authorised as a medicine in Ireland, the UK or the EU.
Current research areas
Published investigation clusters around a small number of biological themes. Each remains experimental and none has been established as a therapeutic effect in humans.
- BDNF and NGF expression measurement
- Cerebral ischaemia models
- Attention and memory endpoints in rodents
- Dopaminergic and serotonergic system studies
Scientific context and proposed mechanisms
Increased expression of brain-derived neurotrophic factor and its receptor is the mechanism most often cited, with the ACTH-derived sequence reported to act without the corticotropic activity of the parent hormone.
Interpreting the evidence
Most published work in this area uses cell culture or rodent models with small group sizes and short observation windows. Independent replication varies considerably between compounds, and results are sensitive to species, route, dose and endpoint.
There is no regulatory-approved human protocol for this compound. Any laboratory protocol should be defined by the model under study, institutional ethical approval, appropriate controls and predefined endpoints.
References
CERTIFICATE OF ANALYSISIndependent batch testing
Every released batch is independently tested. Match the batch number on the vial to the certificate published online.
- Batch number
- KL-SEMAX-2406A
- Testing laboratory
- Colmaric Analyticals
- Date tested
- 9 June 2026
- Reported purity
- 99.21%
- Method
- RP-HPLC with UV detection at 214 nm, confirmed by LC-MS
