Description
OVERVIEWProduct overview
KPV is the C-terminal tripeptide of alpha-MSH. It retains much of the anti-inflammatory activity described for the parent hormone in laboratory models while lacking its pigmentary action.
Most published work concerns intestinal epithelial cultures and rodent colitis models, where the peptide has been examined in relation to cytokine signalling and epithelial barrier integrity.
All findings are preclinical. KPV is not an authorised medicine.
SUPPLY IN IRELANDKPV Ireland — supplied to research laboratories
Research groups across Ireland buy KPV from Kensington Laboratories as a lyophilised KPV peptide, released only against a batch-matched certificate of analysis. Every vial of high purity KPV is verified by HPLC and LC-MS before it leaves the facility, so laboratories ordering KPV in Ireland receive material with documented purity and identity.
Laboratory KPV is packed for controlled storage and sent by tracked delivery in 3–5 days to Dublin, Cork, Galway, Limerick and the rest of Ireland. Delivery costs €9.90 per order. Teams planning KPV research can review the specifications, certificate of analysis and reference list on this page before ordering.
Institutions searching for KPV peptide suppliers in Ireland typically compare purity, batch documentation and delivery times. Each of those is published here: a 99% HPLC purity specification, a certificate matched to the batch code on your vial, and tracked delivery in 3–5 days.
KPV is supplied strictly for laboratory research use only. It is not a medicine and is not for human or veterinary consumption.
SPECIFICATIONSProduct specifications
- Purity: ≥ 99% (HPLC)
- Appearance: White lyophilised powder
- Quantity: 5 mg or 10 mg per vial
- CAS number: 67727-97-3
- Sequence: Lys-Pro-Val
- Peptide class: Tripeptide fragment of alpha-melanocyte-stimulating hormone
- Also known as: Lysine-proline-valine, alpha-MSH (11-13)
- Solubility: Soluble in bacteriostatic or sterile water
- Storage temperature: Store at 2–8°C; long-term −20°C, protected from light
- Shelf life: 24 months lyophilised; 30 days reconstituted at 2–8°C
- Manufacturing standard: ISO 9001 facility, GMP-aligned solid-phase synthesis
- Batch information: Batch number and expiry printed on every vial label
RESEARCHResearch overview
The following summary is provided for educational and scientific context only. It describes what has been observed in published laboratory and animal studies and does not represent established clinical outcomes, medical advice or a claim of efficacy in humans.
Background
KPV is the C-terminal tripeptide of alpha-MSH. It retains much of the anti-inflammatory activity described for the parent hormone in laboratory models while lacking its pigmentary action.
Most published work concerns intestinal epithelial cultures and rodent colitis models, where the peptide has been examined in relation to cytokine signalling and epithelial barrier integrity.
All findings are preclinical. KPV is not an authorised medicine.
Current research areas
Published investigation clusters around a small number of biological themes. Each remains experimental and none has been established as a therapeutic effect in humans.
- NF-κB signalling in epithelial cell culture
- Rodent colitis and gut barrier models
- Pro-inflammatory cytokine measurement
- Topical and dermal inflammation research
Scientific context and proposed mechanisms
Authors describe uptake of the tripeptide by intestinal epithelial cells through peptide transporters, followed by reduced NF-κB pathway activation and lower measured cytokine output.
Whether the same route applies in other tissues is not established.
Interpreting the evidence
Most published work in this area uses cell culture or rodent models with small group sizes and short observation windows. Independent replication varies considerably between compounds, and results are sensitive to species, route, dose and endpoint.
There is no regulatory-approved human protocol for this compound. Any laboratory protocol should be defined by the model under study, institutional ethical approval, appropriate controls and predefined endpoints.
References
CERTIFICATE OF ANALYSISIndependent batch testing
Every released batch is independently tested. Match the batch number on the vial to the certificate published online.
- Batch number
- KL-KPV-2406A
- Testing laboratory
- Colmaric Analyticals
- Date tested
- 9 June 2026
- Reported purity
- 99.31%
- Method
- RP-HPLC with UV detection at 214 nm, confirmed by LC-MS
