Description
OVERVIEWProduct overview
Dermorphin was originally isolated from the skin of South American frogs of the genus Phyllomedusa. It is notable for containing a D-amino acid, which is unusual in animal-derived peptides.
In pharmacology it is used as a highly selective mu-opioid receptor reference ligand in binding and functional assays.
It is a controlled research reagent in many jurisdictions and is supplied strictly for laboratory use by qualified professionals.
SUPPLY IN IRELANDDermorphin Ireland — supplied to research laboratories
Research groups across Ireland buy Dermorphin from Kensington Laboratories as a lyophilised Dermorphin peptide, released only against a batch-matched certificate of analysis. Every vial of high purity Dermorphin is verified by HPLC and LC-MS before it leaves the facility, so laboratories ordering Dermorphin in Ireland receive material with documented purity and identity.
Laboratory Dermorphin is packed for controlled storage and sent by tracked delivery in 3–5 days to Dublin, Cork, Galway, Limerick and the rest of Ireland. Delivery costs €9.90 per order. Teams planning Dermorphin research can review the specifications, certificate of analysis and reference list on this page before ordering.
Institutions searching for Dermorphin peptide suppliers in Ireland typically compare purity, batch documentation and delivery times. Each of those is published here: a 99% HPLC purity specification, a certificate matched to the batch code on your vial, and tracked delivery in 3–5 days.
Dermorphin is supplied strictly for laboratory research use only. It is not a medicine and is not for human or veterinary consumption.
SPECIFICATIONSProduct specifications
- Purity: ≥ 99% (HPLC)
- Appearance: White lyophilised powder
- Quantity: 5 mg per vial
- CAS number: 77614-16-5
- Sequence: Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser
- Peptide class: Naturally occurring heptapeptide containing D-alanine
- Also known as: Amphibian opioid heptapeptide
- Solubility: Soluble in bacteriostatic or sterile water
- Storage temperature: Store at 2–8°C; long-term −20°C, protected from light
- Shelf life: 24 months lyophilised; 30 days reconstituted at 2–8°C
- Manufacturing standard: ISO 9001 facility, GMP-aligned solid-phase synthesis
- Batch information: Batch number and expiry printed on every vial label
RESEARCHResearch overview
The following summary is provided for educational and scientific context only. It describes what has been observed in published laboratory and animal studies and does not represent established clinical outcomes, medical advice or a claim of efficacy in humans.
Background
Dermorphin was originally isolated from the skin of South American frogs of the genus Phyllomedusa. It is notable for containing a D-amino acid, which is unusual in animal-derived peptides.
In pharmacology it is used as a highly selective mu-opioid receptor reference ligand in binding and functional assays.
It is a controlled research reagent in many jurisdictions and is supplied strictly for laboratory use by qualified professionals.
Current research areas
Published investigation clusters around a small number of biological themes. Each remains experimental and none has been established as a therapeutic effect in humans.
- Mu-opioid receptor binding and selectivity assays
- D-amino acid peptide stability research
- Receptor pharmacology reference standards
- Comparative opioid peptide studies
Scientific context and proposed mechanisms
The peptide binds the mu-opioid receptor with high selectivity, which is why it is used as a reference ligand in receptor characterisation work.
The D-alanine residue confers resistance to peptidase degradation relative to all-L sequences.
Interpreting the evidence
Most published work in this area uses cell culture or rodent models with small group sizes and short observation windows. Independent replication varies considerably between compounds, and results are sensitive to species, route, dose and endpoint.
There is no regulatory-approved human protocol for this compound. Any laboratory protocol should be defined by the model under study, institutional ethical approval, appropriate controls and predefined endpoints.
References
CERTIFICATE OF ANALYSISIndependent batch testing
Every released batch is independently tested. Match the batch number on the vial to the certificate published online.
- Batch number
- KL-DERMORPHIN-2406A
- Testing laboratory
- Colmaric Analyticals
- Date tested
- 9 June 2026
- Reported purity
- 99.31%
- Method
- RP-HPLC with UV detection at 214 nm, confirmed by LC-MS
The independent result for this batch is summarised above. Contact the laboratory team if you need the full report for this batch.
